AN INVESTIGATION ON THE IMPACT OF ORALLY ADMINISTERED CELERY AND ORANGE JUICES ON THE PRODUCTION OF COLLAGEN IN RATS EXPOSED TO ULTRAVIOLET-B LIGHT

ADLI ARHANI (2023) AN INVESTIGATION ON THE IMPACT OF ORALLY ADMINISTERED CELERY AND ORANGE JUICES ON THE PRODUCTION OF COLLAGEN IN RATS EXPOSED TO ULTRAVIOLET-B LIGHT , TESIS, UNIVERSITAS PRIMA INDONESIA

ABSTRAK

Wounds inevitably occur in everyone. This study investigates whether a cream prepared from Moringa (Moringa oleifera) leaf extract can accelerate wound healing caused by wounds. Moringa leaf (Moringa oleifera) is one of the many plant-based medicines used to reduce pain and accelerate wound healing. Laboratory experiment or real experiment with pre-post test with control group was used. Adult Wistar rats (Rattus norvegicus) were used. During the study, phytochemicals were tested, rats were acclimatized, and they were treated with wound dressings. In this study, after the mice had been exposed to UVB light, they were then given celery juice (Apium graveolens) or orange juice (Citrus) orally to find out if both types of juice would increase the level of collagen in their bodies. Learning in a controlled laboratory or doing the right experiment is a choice. Twenty-four mice including eight white mice in each group. The results showed that the phytochemical tests that have been found in celery and orange juice have therapeutic potential due to the high concentration of antioxidant components. The group that has been given orange juice will have a greater impact on the collagen growth of the mouse skin tissue after exposure to UVB light than the group given celery juice. This is because their skin has a collagen density value of 3+ and a collagen fiber density of 50 to 90% per field of view

JURNAL