SCREENING OF DRUG INTERACTION PRESCREPTION FOR OUTPATIENTS WITH DIABETES MELLITUS AND HYPERTENSION FROM OCTOBER TO DECEMBER 2023 AT ADVENT HOSPITAL MEDAN
TISA KHAIRATUNAWA (2025) SCREENING OF DRUG INTERACTION PRESCREPTION FOR OUTPATIENTS WITH DIABETES MELLITUS AND HYPERTENSION FROM OCTOBER TO DECEMBER 2023 AT ADVENT HOSPITAL MEDAN , SKRIPSI, UNIVERSITAS PRIMA INDONESIA
ABSTRAK
Diabetes mellitus and hypertension are two chronic
conditions that frequently occur simultaneously and
require long-term pharmacological therapy. The
combination of treatments in patients with both diseases
increases the potential for drug interactions, which can
compromise therapeutic effectiveness and elevate the risk
of adverse effects. This study aimed to evaluate the
severity of drug interactions in outpatients with diabetes
mellitus and hypertension at Advent Hospital Medan
during the period from October to December 2023. A non-
experimental descriptive study with a cross-sectional
design was employed, using retrospective data from 191
outpatient prescriptions that met the inclusion criteria.
Evaluation was conducted on administrative,
pharmaceutical, and clinical aspects of the prescriptions,
with a primary focus on identifying drug interactions
using the reference database Drugs.com. The results
showed that drug interactions were present in 52.4% of the
analyzed prescriptions. Most interactions were classified
as moderate in severity, predominantly involving
pharmacodynamic mechanisms. The most frequent
interacting drug combinations included metformin,
glimepiride, amlodipine, bisoprolol, and candesartan. The
high prevalence of drug interactions among patients with
diabetes mellitus and hypertension highlights the
importance of systematic prescription screening as a
preventive measure. These findings can serve as a basis for
developing rational drug use policies and enhancing
patient safety in clinical practice.
JURNAL
| KATEGORI JURNAL | Jurnal Nasional Terakreditasi |
|---|---|
| TAHUN JURNAL | 2025 |
| VOLUME JURNAL | 3 |
| NOMOR JURNAL | 1 |
| NAMA PENERBIT | Nusantara Scientific Medical Research Journal |
| NOMOR ISSN/ISBN | 2985 – 3508 |
| LAMAN PENERBIT (URL) | https://nusantarascientificjournal.com/index.php/nsmrj/index |
| LAMAN ARTIKEL (URL) | https://nusantarascientificjournal.com/index.php/nsmrj/article/view/101/version/101 |