ETHANOLIC EXTRACT OF SYZYGIUM POLYANTHUM EFFECT IN REDUCE BIOMARKERS LEVELS TO PREVENT RATS LIVER DAMAGE

NORMA ELMAWATI NIDYA SARI (2021) ETHANOLIC EXTRACT OF SYZYGIUM POLYANTHUM EFFECT IN REDUCE BIOMARKERS LEVELS TO PREVENT RATS LIVER DAMAGE , TESIS, UNIVERSITAS PRIMA INDONESIA

ABSTRAK

The liver is the biggest solid internal organ and gland. It is also one of the most critical and complex organs, acting as a hub for food metabolism and metabolite excretion. The structure and function of the organ may be impaired by benzene, a pollutant in the environment. Bay leaves, which have been used as a spice and historically to cure various illnesses by Indonesian culture, are one of the medicines that are the subject of this article. It has numerous pharmacological advantages, including anti-cancer, anti-hyperlipidemia, and high antioxidant action. As a result, the purpose of this research is to evaluate the advantages of ethanolic extract of bay leaves and their hepatoprotective impact in benzene-induced rats. As samples, healthy rats were administered the extract for 21 days at doses of 400, 600, and 800 mg/kgBW. They were given benzene injections every 3 and 6 days. The findings indicated that the ethanolic extract of bay leaves may prevent liver damage by lowering levels of biomarkers such as AST, ALT, ALP, GGT, Albumin, and Billiburin, which were statistically different (p0.05) in this research. As a result, it was determined that bay leaves had hepatoprotective action.

 

PROSIDING

KATEGORI PROSIDING	Prosiding Internasional
LOKASI PROSIDING	MEDAN
TANGGAL MULAI KONFERENSI	2021-07-14
TANGGAL SELESAI KONFERENSI	2021-07-16
NAMA PENERBIT	IEEE
NOMOR ISSN/ISBN	9781665441827
LAMAN PENERBIT (URL)	https://ieeexplore.ieee.org/Xplore/home.jsp
LAMAN ARTIKEL (URL)	http://ieeexplore.ieee.org/document/9537278