ANALYSIS OF PACKED RED CELL (PCR) STORAGE TIME AGAINST CHANGES IN ROUTINE BLOOD VALUES IN THE BLOOD DONOR UNIT OF INDONESIAN RED CROSS SOCIETY MEDAN CITY

EKA SYAFRIDA (2022) ANALYSIS OF PACKED RED CELL (PCR) STORAGE TIME AGAINST CHANGES IN ROUTINE BLOOD VALUES IN THE BLOOD DONOR UNIT OF INDONESIAN RED CROSS SOCIETY MEDAN CITY , TESIS, UNIVERSITAS PRIMA INDONESIA

ABSTRAK

Background. Modern blood transfusion therapy now uses blood components to give a specific part of the blood according to clinical indications. Transfusion of blood components such as Packed Red Cell (PRC) can reduce the risk of unwanted transfusion  reactions for the recipient. Requests for patient needs that come in through Hospital Blood  Banks (HBB) requests to the Indonesian Red Cross Society Medan Blood Donor Unit cover 70% of the PRC components, while the rest are other blood components. Several HBB in collaboration with Blood Donor Unit Indonesian Red Cross Society of Medan City impose a maximum time limit for storing PRC that has been processed from Whole Blood (WB), which is two days from processing PRC. Still, some ask for a maximum of 7 days from processing.

Objective. To analyze the effect of Packed Red Cell (PRC) storage time on changes in routine blood values.

Method. This type of research is a quantitative analytical study with comparative numerical more than two groups to analyze the storage time of PRC blood on changes in routine blood values.

Result. The study was conducted with 40 research subjects. The measurement parameters were leukocytes, haemoglobin, and hematocrit. The examination results for erythrocytes obtained a p-value<0.05; this indicates that there is a significant difference between erythrocytes and PRC storage. The longer the storage time, the lower the erythrocyte value. Compared with the storage of erythrocytes on day 1, it showed a decrease in the value of erythrocytes compared to the storage of erythrocytes on day 11. For haemoglobin examination results obtained p-value<0.05, this indicates a significant difference in haemoglobin against PRC storage on day 1 today 1. 11, where if the storage time is longer, the haemoglobin value will increase. For the results of the examination of hematocrit levels, p-value<0.05, this indicates a significant difference in hematocrit against PRC storage on day 1 today 11, where if the storage time is longer, the hematocrit value increases.

Conclusion. Haemoglobin and hematocrit levels, there was a significant increase in changes and erythrocytes during the eleven-day storage process, a significant decrease but still within normal limits.

JURNAL

KATEGORI JURNAL	Jurnal Internasional
TAHUN JURNAL	2022
VOLUME JURNAL	9
NOMOR JURNAL	4
NAMA PENERBIT	Journal of Innovations in Pharmaceutical and Biological Sciences (JIPBS)
NOMOR ISSN/ISBN	23492759
LAMAN PENERBIT (URL)	https://jipbs.com/index.php/journal/index
LAMAN ARTIKEL (URL)	https://jipbs.com/index.php/journal/article/view/438