POTENSI ANTIOKSIDAN DAN ANTI-ELASTASE EKSTRAK DAUN KELOR ( MORINGA OLEIFERA ) TERHADAP ANTIAGING

GLORIO IAS NATANAEL, GIDION FRANKLIN SIMORANGKIR, NANDA PARARISKI PURBA, MARDIANA PUTRI BR. TAMBUNAN (2021) POTENSI ANTIOKSIDAN DAN ANTI-ELASTASE EKSTRAK DAUN KELOR ( MORINGA OLEIFERA ) TERHADAP ANTIAGING , SKRIPSI, UNIVERSITAS PRIMA INDONESIA

ABSTRAK

ABSTRACK

Skin aging causes by oxidative stress that leads to formation on wrinkles, pigmentation, and asteatosis. On the other hand, elastase enzyme also can influence the elasticity of the skin that leads to sagging. Moringa leaves (Moringa oleifera Lamk)  has been reported contain some active compounds like flavonoid that has antioxidant and anti-aging potential. This study was presented to determine the potential of moringa leaves extract (MLE) in scavenging DPPH radical and inhibiting the elastase enzyme. MLE was obtained by using maceration methods. The potential of MLE in scavenging DPPH radical and inhibiting elastase enzyme was determine using spectrophotometric methods. MLE has IC₅₀ value of DPPH scavenging activity also elastase inhibitory activity at 109.67 + 0.83 µg/mL and 159.67 + 7.95 µg/mL. MLE has antioxidant and anti-aging potential as indicated by DPPH scavenging activity and elastase inhibitory. However, MLE has moderate DPPH scavenging activity and low elastase inhibitory activity. 

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